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Even if no analysis of lipids was performed in this study, evidence obtained in the epifluorescence experiments carried out with ‘ F

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3.1.2 Mechanism of lipid peroxidation-mediated ferroptosis involved in ischemic stroke As outlined, lipid peroxidation, particularly the conversion of PUFAs in the phospholipid bilayer to L-OOHs, is a crucial mechanism of ferroptosis and plays a significant role in the development of IS